What would you regard as unwinnable culture wars? To my mind there's no such thing. As you say, if you sink in the decades, you can swing it back your way.
I haven't posted in a long while since I'm still waiting to see how those races in Nevada & Arizona shake out - apparently the GOP can still win both governorships and Senate seats, which would mean they could afford to lose the Georgia runoff if they manage it - but I gotta say, I'm 100% in agreement with this sentiment. 50 years ago things like gay marriage, 'shouting your abortion' or acceptance of drug use would have been unimaginable, and that was still the case 30 years ago. Hell not 15 years ago, freaking California of all places (long after it had shifted interminably blue even!) voted against the former.
It takes time to change the culture one way or the other but it can be done, and sometimes it can happen really quickly if the excesses of one side or the other are too much to bear. Setting aside the obvious example of Germany flying from rampant child prostitution and being Ground Zero for the
Institut für Sexualwissenschaft & sexual revolution to electing Literally Hitler and putting Hirschfeld's books to the torch in 10 years, England going from the Puritanism of the Cromwellian dictatorship to the hedonistic licence of the Restoration in a similar timeframe or snapping from the decadence and rationalism of the Regency Era to the much stricter moral standards and romanticism of the Victorian period all come to mind. Or for more contemporary examples, the Eastern European countries enslaved by Communism tend to be vastly more conservative than the capitalist Western Europeans, as well.
I say this because I've noticed a trend to blame the Dobbs case (the one that overturned Roe v. Wade) for the GOP's underperformance cropping up on some of my online haunts.
But all the governors who actually passed abortion restrictions (or full-on banned it with exemptions for rape, incest and/or the mother's life won their elections, often quite overwhelmingly - even hardliners. Just giving up on the Right's first real cultural victory since the start of the Cold War less than half a year of it happening because a midterm (in a cycle which doesn't even favor Republicans!) not even necessarily went bad, just underperformed expectations, is the stupidest take I've seen this week - getting wiped out in 2010 and taking a slightly less awful beating in 2014 hardly stopped or even significantly slowed Obama's progressive agenda, for examples on the other side of the coin.
Obviously pushing for a nationwide
'human life amendment' is not viable in the short term after 50 years and multiple generations growing up with abortion on demand being the law of the land, barring the Fifth Great Awakening or some other Georgian-->Victorian snapback in the culture happening soon. But a more pragmatic strategy of pushing the envelope only as far right as possible in states with Republicans in control (ex. the tightest ban makes sense in ruby-red South Dakota while one with more exceptions makes more sense in a purpler state like North Carolina), maintaining a right-leaning 'state-by-state but we obviously favor a lean to the right' policy on the national level, and working to expel wokeness from & restore respect for the sanctity of life within the educational system so as to induce a cultural reversion toward the latter long-term (and thus an atmosphere where a human life amendment actually becomes possible) while focusing on cultural battles where the present atmosphere is more favorable to conservatism (like transgender bathrooms and sports) is the way to go, not waving the white flag immediately after SCOTUS just handed the Right its first real win in the culture war in ages.
Tl;dr now that Republicans can no longer just virtue signal about being pro-life, secure in the knowledge that the courts will slap down anything they actually try to do about abortion, but actually must
be pro-life (and that their socially conservative constituents can reasonably expect action on this front), it's time for a new strategy. And they should much rather look to how their party handled slavery in 1854-60 than just give up on yet another, perhaps the biggest, front in the culture war: notably neither Fremont nor Lincoln declared an intent to outlaw slavery immediately nationwide in their platforms, because they knew that wouldn't win anywhere outside of abolitionist New England then (just as pushing for an HLA wouldn't win anyplace outside of deep red bastions like the Dakotas or Oklahoma), but they still pushed the envelope where they could and activists like Harriet Beecher Stowe & Frederick Douglass worked to shift the culture. Politics is the art of the possible, the Democrats of the 1970s didn't come out swinging with unlimited 9-month and even post-birth abortions, drag queen story hour & abolishing whiteness either after all.