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I saw a design for nuclear powered spaceship some time ago, heat dissipation system took most of the volume.

Of course the time can be expedited if you do it in an enclosed system, add some bacteria and ramp up the heat a bit.

Human manure needs to be composted for at least a year, to kill off the harmful bacteria inside, same for manure of other omnivores like pigs and chicken.

It's a future fiction, we must simply assume there are some advances that made soil depletion thing of a past, so the problems we have don't concern them.