It can as long as it can... Think of silly logistical messes like the recent one though. The more reliant on imports you are, the bigger chance you will feel it.Israel can import its food, no? And life in Ma'ale Adummim or, for that matter, Pisgat Ze'ev is not that bad. I myself previously lived in Pisgat Ze'ev more than two decades ago back when I and my family still lived in Israel.
Living in an area that's surrounded by the West Bank in three directions is not necessarily a bad thing since you're probably not going to be travelling much to the West Bank, if at all, unless perhaps you want to visit the Dead Sea. Your main travelling will be within the Jewish Jerusalem metropolitan area and, of course, into other parts of Israel.
Also an area like this can only seem fine as long as no one does anything stupid. The moment someone does something stupid, and you know that in this region it happens at least every few decades, it's going to be the bumper zone for whatever happens.